Friday Sep 5, 2025
12-16.00 Arrival and registration
Session I Oncogenic Signalling networks
16.00-16.25 Joseph Schlessinger, Yale University, USA, “Developing kinase modulators for cancer therapeutics”
16.30-16:55 Tony Hunter, SALK Institute, USA, “A journey from phosphotyrosine to phosphohistidine and beyond“
17.00-17.25 Letizia Lanzetti, Torino University, “Oncogenic trafficking”
17.30-17.55 Pier Paolo DiFiore, EIO, “Stemness in cancer”
18.00-18.25 Ivan Dikic, Goethe University, Germany, “Cryptic splicing in MYC-amplified tumors“
19:00 – 23:00 Welcome Dinner and poster session 1
Saturday Sep 6, 2025
Session II Tumor Metabolic Rewiring
09.00-09.25 Serkan Kir, Koç University “EDA2R signaling in tumor-induced muscle wasting”
09.30-09.55 Sara Sigismund, IEO, Milan “Endocytic control of cell plasticity in cancer”
10.00-10.15 Selected talk
10.15-10.30 Selected talk
10.30 -11.00 Tea Break
11.00-11.25 Almut Schulze, DFKZ, Germany, “Targeting lipid metabolism in cancer”
11.30-11.55 Ruth Palmer, University of Goteborg, “Metabolic landscape in childhood neuroblastoma”
12.00-12.25 John Scott, University of Washington, “AKAP signaling and tumor metastasis”
12.25-12.45 Flash talks (15)
12.45-15.30 Lunch break and free time
Session III Oncogenic Signaling and Genome Instability
15.30-15.55 Ofer Shoshani, Weizmann, Israel, “Mechanisms and consequences of chromosome catastrophes in cancer”
16.00-16.25 Samual Bakhoum, MSKCC, USA, “How chromosomal instability drives tumor progression”
16.30-16.55 Iva Tolić, RUĐER BOŠKOVIĆ Institute, Croatia, “Mechanobiology of mitosis and its role in mitotic fidelity”
17.00-17.20 Break
17.20-17.45 René Bernards, NKI, Netherlands, “Combination therapies targeting RAS mutant tumors”
17.50-18.15 Geert Kops, Hubrecht Institute, “Chromosome segregation”
18.20-18.45 Dennis Kappei, CSI, Singapore, “Give me a break – how telomere-driven genomic instability contributes to carcinogenesis”
19.00-22.30 Dinner and Poster session II
Sunday Sep 7, 2025
Session IV Cellular Plasticity in Cancer
09.00-09.25 Maria Sibilia, Medical University of Vienna, “Microenvironmental drivers of inflammation and tumorigenesis: Modulating innate immune cell signaling to enhance anti-cancer therapy”
09.30-09.55 Daniela Krause, Uni Mainz “Targeting bone marrow microenvironment in leukemia”
10.00-10.25 Cedric Blanpain, ULB Brussels ”Mechanisms regulating tumor transition states”
10.30-11.00 Tea Break
11.00-11.25 Krishna Rajalingam, Mainz University, “Ras/Raf pathway in Cancers”
11.30-11.55 Roger Daly, Monash University, “Pseudokinases in Cancer”
12.00-12.15 Selected talk
12.15-12.35 Flash talks (15)
13.00-16.00 Lunch and poster session III
16.30-23.00 Excursion to Dubrovnik and free for Dinner
Monday Sep 8, 2025
Session V Tumor Microenvironment and Metastasis
09.00-09.25 Gillian Griffiths, MRC, Cambridge, UK, “T cells in cancer: Control of Secretion at the Immunological Synapse”
09.30-09.55 Marta Miacynska, IIMCB Warscaw, Poland, “Targeting AXL-dependent Trafficking and Signaling in Oncogenesis”
10.00-10.25 Janos Terzic, University of Split, Croatia, “Gut microbiota carcinogen metabolism and tumor metastasis”
10.30-11.00 Tea Break
11.00-11.25 EMBO YIP lecture: Colinda Scheele, VIB – KU Leuven, Belgium. “Intravital imaging and dynamics of tumour progression”
11.30-11.55 Angel Lopez, Adelaide University, “Cytokine signaling and tumor metastasis”
12.00-12.15 Selected talk
12.15-12.30 Selected talk
13.00-16.00 Lunch and free time
Session VI Therapy sensitivity and resistance
16.00-16.25 Stuart Pitson, University of South Australia, Australia, “Therapy resistance mechanisms in myeloid cancers”
16.30-16.55 Mike Yaffe, MIT Center for Precision Cancer Medicine, USA, “CRISPR-Based Screening Reveals Mechanisms of Chemotherapy Sensitization and Resistance in Glioblastoma and Ovarian Cancer”
17.00-17.25 Johanna Ivaska, University of Turku, Finland, “Tumour-stroma crosstalk mediated regulation of drug sensitivity and metastasis”
17.30-17.45 Selected talk
17.45-18:10 Anwesha Dey, Genentech, USA, “Targeting the Hippo Pathway in Cancers.”
20.00 Farewell dinner
Tuesday Sep 9, 2025
Session VII Emerging therapeutics and diagnostics
09.30-09.55 Connie Jimenez, UMC-Cancer Center, Netherlands, “Phosphoproteomics for target discovery and treatment response prediction in cancer”
10.00-10.25 Wee Wei Tee, IMCB,“Targeting transcriptional dysregulation in cancer: Insights from early development” EMBO Global Investigator
10.30-10:55 Paul Timpson, Garvan Intitute, Australia, ”Intravital imaging of pancreatic cancer response using live biosensors imaging”
11.00-11.30 Tea Break
11.30-11.55 Madelon Maurice, UMC Utrecht & Oncode Institute, NL, “SureTACs: targeting membrane protein degradation in cancer”
12.00-12.25 Anguraj Sadanandam, ICR, UK, “Immune, Stromal and Metabolic Heterogeneity in Pancreatic Cancer and its Impact on Therapeutic Responses”
12.30-12.25 Closing ceremony and final remarks
Lunch and Departure